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Aaeg1200g Analyses

This repository contains a subset of the analyses supporting Crawford et al., Science 2025. It includes a collection of scripts, notebooks, and results focused on population genomics of Aedes aegypti and contains the analyses pertaining to insecticide resistance, admixture, and global migration patterns as described in the paper.

Contents

  • analyses/: analysis scripts and notebooks for insecticide resistance, admixture and migration inference
  • containers/: docker / singularity containers used in workflows
  • reports/: summary tables, figures, and intermediate outputs
  • resources/: environment and dependency specifications to reproduce analyses
  • results/: processed results deriving from workflow routines
  • workflows/: snakemake workflows for data processing and analysis

Notes

  • This repository is intended to provide reproducible code and derived results that accompany Crawford et al., Science 2025. For raw genomic data and larger datasets, see the data availability statement in the manuscript.
  • Please follow the LICENSE and CITATION files in the repo when re-using code or results.

Contact For questions about the analyses, please contact the corresponding author listed in Crawford et al., Science 2025.

If reusing any analyses in this repository, please reference:
Crawford, Jacob E., et al. 2025. “1206 Genomes Reveal Origin and Movement of Aedes Aegypti Driving Increased Dengue Risk.” Science (New York, N.Y.) 389 (6766): eads3732.

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Admixture and contemporary migration inference for Aedes aegypti [Crawford et al, Science, 2025]

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