Releases: PathoGenOmics-Lab/pathotypr
Releases · PathoGenOmics-Lab/pathotypr
Pathotypr v1.0.0
First Release
First stable release of Pathotypr — harmonised MTBC lineage assignment and resistance-associated variant detection for genomic surveillance.
Highlights
- 14 MTBC lineages supported: L1–L10, A1–A4
- Alignment-free classification from assemblies and raw reads (FASTQ)
- Drug resistance genotyping using WHO mutation catalogue (grades 1–2)
- Closest-reference matching for improved mapping quality
- Desktop GUI + command-line interface
- Pre-trained Random Forest model (k=31, 100% accuracy on independent validation)
Downloads
| Platform | File |
|---|---|
| macOS Apple Silicon | Pathotypr_1.0.0_aarch64.dmg |
| macOS Intel | Pathotypr_1.0.0_x64.dmg |
| Windows | Pathotypr_1.0.0_x64-setup.exe / .msi |
| Linux | .deb / .rpm / .AppImage |
Data
Lineage markers, DR markers and pre-trained model available at Zenodo (10.5281/zenodo.19210044).
Citation
Ruiz-Rodriguez P, Coscollá M. Pathotypr: harmonised MTBC lineage assignment and resistance-associated variant detection for genomic surveillance. bioRxiv (2026). BIORXIV/2026/714002.
License
AGPL-3.0
See CHANGELOG for details.