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Releases: PathoGenOmics-Lab/pathotypr

Pathotypr v1.0.0

25 Mar 11:11
29d8110

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First Release

First stable release of Pathotypr — harmonised MTBC lineage assignment and resistance-associated variant detection for genomic surveillance.

Highlights

  • 14 MTBC lineages supported: L1–L10, A1–A4
  • Alignment-free classification from assemblies and raw reads (FASTQ)
  • Drug resistance genotyping using WHO mutation catalogue (grades 1–2)
  • Closest-reference matching for improved mapping quality
  • Desktop GUI + command-line interface
  • Pre-trained Random Forest model (k=31, 100% accuracy on independent validation)

Downloads

Platform File
macOS Apple Silicon Pathotypr_1.0.0_aarch64.dmg
macOS Intel Pathotypr_1.0.0_x64.dmg
Windows Pathotypr_1.0.0_x64-setup.exe / .msi
Linux .deb / .rpm / .AppImage

Data

Lineage markers, DR markers and pre-trained model available at Zenodo (10.5281/zenodo.19210044).

Citation

Ruiz-Rodriguez P, Coscollá M. Pathotypr: harmonised MTBC lineage assignment and resistance-associated variant detection for genomic surveillance. bioRxiv (2026). BIORXIV/2026/714002.

License

AGPL-3.0
See CHANGELOG for details.