Configure billionRunOptimized for 1 billion patients

Author: watilde

research/modules/5-billion-scale-polypharmacy/src/billionRunOptimized.js

@@ -16,12 +16,12 @@ const path = require('path');
 const os = require('os');
 
 const CONFIG = {
-  totalPatients: 100_000_000,     // 100 Million (validation run)
-  nSites: 100,                    // 100 sites
+  totalPatients: 1_000_000_000,   // 1 Billion (final run!)
+  nSites: 1000,                   // 1000 sites
   patientsPerSite: 1_000_000,     // 1M per site
   batchSize: os.cpus().length,    // Use all CPU cores
-  outputDir: path.join(__dirname, '../results/optimized_run'),
-  checkpointInterval: os.cpus().length,
+  outputDir: path.join(__dirname, '../results/optimized_1billion_run'),
+  checkpointInterval: os.cpus().length * 10,  // Checkpoint every 10 batches
 };
 
 class OptimizedBillionRunner {